Overview
In this trial, investigators are looking at how exocrine pancreatic insufficiency (EPI) is present in patients with bloating or diarrhea. They will see if early detection and management of EPI will help relieve symptoms and see if it is the main cause of those symptoms. Investigators will include fecal elastase-1 in the tests for patients presenting with diarrhea and/or bloating.
Study Information
In this study, investigators will recruit 200 participants from the St. Luke Baylor’s Clinic during their clinic visit.
Inclusion Criteria
- Patients aged 18 to 80 years old who presents to the gastroenterology clinic with main complaints of diarrhea
- Patients aged 18-80 years old who presents to the gastroenterology clinic with main complaints of flatulence, and/or bloating
- Patients with known IBS, microscopic colitis or celiac disease diagnosis will be included.
- Patients on Diphenoxylate, loperamide or cholestyramine will be included.
Exclusion Criteria
- Known chronic pancreatitis, recurrent acute pancreatitis or autoimmune pancreatitis.
- Known Pancreatic cancer
- Prior History of distal pancreatectomy or Whipple surgery.
- Prior history of gastric bypass surgery or any Roux en Y gastrojejunal anastomosis.
- Pregnant Patients
Location
Baylor College of Medicine
Houston, Texas, United States, 77030
Contact: Mohamed Othman, MD 713-798-0950 Mohamed.Othman@bcm.edu
Sponsors/Collaborators
Baylor College of Medicine
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